Familial medullary thyroid carcinoma

A malignant tumor of the CALCITONIN - secreting parafollicular C cells of the THYROID that occurs sporadically or as a component of the MULTIPLE ENDOCRINE NEOPLASIA (MEN) type 2 (OMIM: 171400)/familial medullary thyroid carcinoma (FMTC) syndromes. Germline mutations in the RET and NTRK1 genes have been identified. OMIM: 155240

Also Known As:

Medullary thyroid cancer, familial; Thyroid Carcinoma, Familial Medullary; Thyroid cancer, familial medullary

Neoplasms: 1324753
- Hereditary Neoplastic Syndromes: 112
  - Multiple Endocrine Neoplasia: 504
    - Multiple Endocrine Neoplasia Type 2a: 1125
      - Familial medullary thyroid carcinoma: 91
- Multiple Primary Neoplasms: 24
  - Multiple Endocrine Neoplasia: 504
    - Multiple Endocrine Neoplasia Type 2a: 1125
      - Familial medullary thyroid carcinoma: 91
- Neoplasms by Site: 4
  - Head and Neck Neoplasms: 18117
    - Thyroid Neoplasms: 18040
      - Familial medullary thyroid carcinoma: 91
  - Endocrine Gland Neoplasms: 130
    - Thyroid Neoplasms: 18040
      - Familial medullary thyroid carcinoma: 91
    - Multiple Endocrine Neoplasia: 504
      - Multiple Endocrine Neoplasia Type 2a: 1125
        Familial medullary thyroid carcinoma: 91
- Neoplasms by Histologic Type: 2
  - Germ Cell and Embryonal Neoplasms: 4454
    - Neuroectodermal Tumors: 217
      - Neuroendocrine Tumors: 6270
        Neuroendocrine Carcinoma: 1123
        Medullary Carcinoma: 1063
        Familial medullary thyroid carcinoma: 91
  - Glandular and Epithelial Neoplasms: 439
    - Carcinoma: 141855
      - Adenocarcinoma: 58365
        Neuroendocrine Carcinoma: 1123
        Medullary Carcinoma: 1063
        Familial medullary thyroid carcinoma: 91
    - Neoplasms, Ductal, Lobular, and Medullary
      - Medullary Carcinoma: 1063
        Familial medullary thyroid carcinoma: 91
  - Nerve Tissue Neoplasms: 1
    - Neuroectodermal Tumors: 217
      - Neuroendocrine Tumors: 6270
        Neuroendocrine Carcinoma: 1123
        Medullary Carcinoma: 1063
        Familial medullary thyroid carcinoma: 91
Endocrine System Diseases: 968
- Thyroid Diseases: 6126
  - Thyroid Neoplasms: 18040
    - Familial medullary thyroid carcinoma: 91
- Endocrine Gland Neoplasms: 130
  - Thyroid Neoplasms: 18040
    - Familial medullary thyroid carcinoma: 91
  - Multiple Endocrine Neoplasia: 504
    - Multiple Endocrine Neoplasia Type 2a: 1125
      - Familial medullary thyroid carcinoma: 91
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Hereditary Neoplastic Syndromes: 112
    - Multiple Endocrine Neoplasia: 504
      - Multiple Endocrine Neoplasia Type 2a: 1125
        Familial medullary thyroid carcinoma: 91

L Martorell Sampol Selected Research

L Martorell Sampol Research Topics

Disease

Drug/Important Bio-Agent (IBA)